Instead of a cumbersome and sometimes painful routine drawing of blood, patients with diabetes may be able to use their tears, researchers from the University of Michigan reported in analytical chemistry. In animal studies, researchers found that the level of glucose from the tears of rabbits can accurately measure blood glucose (sugar) levels, using the electrochemical sensor device.
Leading researchers, Mark Meyerhoff and team explained that approximately 5% of people worldwide have diabetes. With increasing levels of obesity worldwide, the number of patients with type 2 diabetes, is set to increase significantly.
The researchers, whether they intend to develop a new, painless device that can detect the tear glucose, instead of having to draw blood.
Patients with diabetes may have to draw blood from two to ten times daily to check their blood glucose levels. A significant number of patients with diabetes, not to draw blood as often as they should, because of discomfort and pain it causes. This can lead to poor glycemic control. Long-term poor glycemic control increases in the number of risks and complications associated with the state, especially microvascular complications, which may lead to the development of neuropathy and foot ulcers, retinopathy and other diseases and conditions.Investigators say that in accordance with their findings, the tears can provide as accurate reading as the choice of the fingers and blood directly.
The authors wrote:
".... It may be possible to measure glucose levels tears several times a day to monitor changes in blood glucose without the pain of repeated potential invasive blood sampling. "
Their sensor is very sensitive and can reach very low detection limits of 1,5 ± 0,4 mmol of glucose (S / N = 3). This is sufficient to measure tear fluid glucose levels in glucose sensitivity of 0,032 ± 0,02 nA / micron. The capillary tube sensor requires only 4-5 ml of tears, when the needle is inserted into the capillary sensor.
As in the journal, the researchers wrote:
"The strong correlation between tear and blood glucose levels was detected, suggesting that the measurement of tear glucose measurement of potential noninvasive substitute blood glucose, and a new configuration of sensor could help in further research in this direction."
Leading researchers, Mark Meyerhoff and team explained that approximately 5% of people worldwide have diabetes. With increasing levels of obesity worldwide, the number of patients with type 2 diabetes, is set to increase significantly.
The researchers, whether they intend to develop a new, painless device that can detect the tear glucose, instead of having to draw blood.
Patients with diabetes may have to draw blood from two to ten times daily to check their blood glucose levels. A significant number of patients with diabetes, not to draw blood as often as they should, because of discomfort and pain it causes. This can lead to poor glycemic control. Long-term poor glycemic control increases in the number of risks and complications associated with the state, especially microvascular complications, which may lead to the development of neuropathy and foot ulcers, retinopathy and other diseases and conditions.Investigators say that in accordance with their findings, the tears can provide as accurate reading as the choice of the fingers and blood directly.
The authors wrote:
".... It may be possible to measure glucose levels tears several times a day to monitor changes in blood glucose without the pain of repeated potential invasive blood sampling. "
Their sensor is very sensitive and can reach very low detection limits of 1,5 ± 0,4 mmol of glucose (S / N = 3). This is sufficient to measure tear fluid glucose levels in glucose sensitivity of 0,032 ± 0,02 nA / micron. The capillary tube sensor requires only 4-5 ml of tears, when the needle is inserted into the capillary sensor.
As in the journal, the researchers wrote:
"The strong correlation between tear and blood glucose levels was detected, suggesting that the measurement of tear glucose measurement of potential noninvasive substitute blood glucose, and a new configuration of sensor could help in further research in this direction."
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